Clinical importance of micrometastasis in sentinel lymph nodes
نویسندگان
چکیده
منابع مشابه
Advantages of the rapid double-staining method for intraoperative detection of micrometastasis in sentinel lymph nodes.
For rapid intraoperative diagnosis of lymph node micrometastasis, we refined the rapid immunohistochemistry method by combining anti-cytokeratin antibody-labeled nanocrystal beads with rapid hematoxylin and eosin (H&E) staining on the same section, referred to as the rapid double staining (RDS) technique. Two frozen-section slices each were obtained from 372 lymph nodes of 100 breast cancer pat...
متن کاملFrozen section in axillary sentinel lymph nodes for diagnosis of breast cancer micrometastasis.
BACKGROUND Sentinel lymph node (SLN) biopsy plays a major role in the surgical management of primary breast cancer. The aim of this study was to assess the diagnostic accuracy of the assessment of axillary frozen sections of SLNs for micrometastasis diagnosis. PATIENTS AND METHODS This study focused on 278 SLNs from 149 patients. Each lymph node was fully analyzed by frozen section. After fix...
متن کاملintra-operative assessment of sentinel lymph nodes in breast cancer
lymph node status remains an important prognostic indicator for survival in breast cancer. sentinel lymph node biopsy has become the standard method of assessment of clinically node negative breast cancers. economic implications as well as patient related factors have lead to the development a number of intra-operative techniques. review of the emerging trends in the last 4 years show that alth...
متن کاملContrast enhanced ultrasound of sentinel lymph nodes
Sentinel lymph nodes are the first lymph nodes in the region that receive lymphatic drainage from a primary tumor. The detection or exclusion of sentinel lymph node micrometastases is critical in the staging of cancer, especially breast cancer and melanoma because it directly affects patient's prognosis and surgical management. Currently, intraoperative sentinel lymph node biopsies using blue d...
متن کاملPathology of sentinel lymph nodes for melanoma.
As a concept sentinel lymph node biopsy seems attractive in that it attempts to identify the first lymph node, rather than the nearest node, draining a particular anatomic area where a tumour has arisen. Pathological assessment can then indicate whether metastases are present and the procedure is either a strong prognostic indicator or possibly therapeutic in itself. These comments apply to any...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Breast
سال: 2011
ISSN: 0960-9776
DOI: 10.1016/j.breast.2010.08.005